Learn About Top 10 Biotech Bay Companies

This year's most innovative companies in biotechnology extend their R&D capabilities to researchers in the lab and online. This enables more comprehensive and accurate diagnostic tests while offering new models for everything from developing drugs to maintaining healthy soil for agriculture.

What Is A Biotech Company?

A biotech company is a company whose products or services primarily use biotechnology methods in production, development, or distribution. Biotech companies mainly operate in the fields of medicine, agriculture, crop production and heavy industry.

Top 10 Biotech Bay Companies

1. TMRW LIFE SCIENCES

IVF clinics around the world actively manage and store millions of frozen human fertility cells, also known as oocytes and embryos. This number is expected to grow to tens of millions in the coming years. Many clinics still handle samples by hand and track patient records using paper records. 

TMRW Life Sciences is the first automated platform for the storage, management and maintenance of frozen oocytes and embryos used in IVF. The integrated software and hardware ensure that eggs and embryos are tracked using radio frequency identification (RFID) technology and securely stored at cryogenic temperatures. While maintaining the optimal temperature for all samples throughout the collection process, robotics and automation enable physicians to collect eggs and embryos. 

Launched in 2021 with leading IVF clinics in Boston, Denver, Chicago and San Diego, TMRW safely transferred over 30,500 existing eggs and embryos onto its platform.

2. STRATA ONCOLOGY

In 2021, Strata commercialized its StrataNGS 429 genetic test, which profiles solid tumors to match cancer patients with the most effective therapies. StrataNGS is unique in its ability to profile tumors from a tiny tissue sample: it requires 10 times less tissue than traditional tumor genome profiling tests and can therefore provide treatment-selective results in 50% or more of patients. 

Two big sponsors are Pfizer Ventures and Merck Global Health Innovation Fund joined in a $90 million Series C funding in July.

3. DNA SCRIPT

Paris-based DNA Script is among the leaders in developing a faster, more precise, and more efficient alternative to traditional chemical DNA synthesis called enzymatic DNA synthesis, or EDS. Important for research purposes, EDS allows the generation of longer DNA strands than other methods. 

With the Syntax System benchtop printer, which was commercially launched in June 2021, scientists of this biotech company can now print their own DNA on-demand in their laboratories. DNA Script is part of a consortium of companies selected by the Intelligence Advanced Research Projects Activity (IARPA) to develop a DNA-based data storage system and their big partners Moderna and GE Research are cooperating to provide on-demand to develop vaccines against bio-threats.

4. EMULATE

In March 2021, biotech company Emulate launched its Colon Intestine chip for researchers studying inflammatory bowel disease. In June 2021, it launched the Emulate Brain chip, a realistic model of cell types in the brain that can be used to study the mechanisms of neuroinflammation and to assess the effectiveness of drug candidates in penetrating the blood-brain barrier. 

This and other so-called organ chips combine different types of living cells on a special microfluidic chip that mimics the natural physiology and mechanical forces that cells in the human body are subjected to. Such chips could replace animal testing in many cases, and Emulate has been an animal rights advocate, pushing legislation to reduce the use of primates for drug testing and supporting the FDA Modernization Act and the Humane Research Act, which call for alternatives to animal testing.

5. LIGHTDECK DIAGNOSTICS

Using a laser and microfluidic platform, LightDeck's cartridge-based testing system allows you to test samples and get results almost anywhere in minutes with lab-quality precision.

In 2021, the company received $35.1 million from the Department of Defense and Health and Human Services to ramp production of its COVID-19 antigen and antibody tests from 50,000 tests per month to 1 million tests per month by September 2022 increase. In May 2021, LightDeck partnered with Hach, a global leader in water systems, to implement 10-minute water quality testing for fast, affordable, lab-quality water testing.

6. BENCHLING

Benchling launched its life sciences R&D cloud platform in 2013, but 2021 was the year it launched and became a hotbed for scientists to collaboratively design, test, and develop complex RNA therapies in a unified environment. Benchling is the first third-party cloud solution built specifically for life sciences and clearly fills a need: Benchling's platform has more than 700 customers, including biopharmaceutical companies like Editas, Regeneron, Gilead, and Pfizer, plus 200,000 researchers at more than 7,000 leading academic and research institutions. One in four new biotech companies going public in 2020 and 2021 was founded on Benchling.

7. MYRIAD GENETICS

In 2021, Myriad, which developed the first test for BRCA gene mutations that may increase breast cancer risk, introduced the first validated polygenic breast cancer risk assessment score for women from diverse populations and all ancestry, which addresses long-standing differences in screening and outcomes for non-white patients. 

Between insurance coverage and Myriad's financial assistance program, nine out of 10 women who qualify for the test pay $0 to ensure broad access, according to Myriad.

8. BIOME MAKERS

Biotech company BiomeMakers, based in Sacramento, California, uses DNA sequencing, bioinformatics, and smart computing to analyze the soil microbiome of analyzing farmland and draws from its database of 27,000 soil microbiome samples from over 60 different crops to provide data-backed insights into what the soil really needs to be healthy for each crop and soil type.

By providing a more complex picture of soil health than traditional chemical tests, Biome Makers enables farmers and product manufacturers to measure the impact of fertilizers and biological inputs or practices on the soil microbiome. The company, which raised a $15 million Series B in August, has 900 individual clients worldwide and has partnerships with Bayer Crop Science, Dole, Marion Ag, and Eurofins.

9. SAFETRACES

Founded in 2013, this Bay Area start-up transitioned from its core business of barcoding DNA to making food and pharmaceuticals traceable through the supply chain to selling a DNA-based test for airborne diseases.

The system uses proprietary “DNA-tagged aerosol tracers” to detect, measure and visualize airflow, ventilation, and filtration anomalies in real-world indoor environments and safely simulate respiratory emission and occupational exposure to infectious diseases like COVID-19. 

Recent clients include the California Department of Justice, the NY/NJ Port Authority, schools, long-term care facilities, and business owner Brookfield Properties. SafeTraces reported 200% revenue growth quarter over quarter in 2021.

10. BRIDGEBIO PHARMA

Using an innovative "portfolio model" for drug development, BridgeBio Pharma operates like a private equity firm risk: A central management team with experience in sales and portfolio management Diversified program items targeting diverse drug and disease platforms, a new paradigm in biotechnology. 

In 2021, the company received its first two FDA approvals for targeted therapies for bile duct cancer and a rare and life-threatening condition known as Molybdenum Cofactor Deficiency (MoCD) type A. These therapies are said to be valuable ones for mankind and open up many bright doors to the future.

Of the 36 new drug approvals, the FDA will grant this year, BridgeBio is one of only four to have more than one; others are established pharmaceutical giants such as Merck, GlaxoSmithKline, and Janssen Pharmaceutical, making BridgeBio the smallest biotech company to achieve this feat. About 20 other drug trials are underway.

Largest Biotech Companies

To identify the world's largest biotech companies, we looked at the two most important fundamental metrics, their market cap, and revenue. The higher the market capitalization, the higher the value of the company. Of course, revenue is another important metric as it basically shows a company's market share, which in turn also reflects the size of the company and its reach in the market.

Not only are these companies huge, but they are also quite profitable, which is why you will also see some names on the list of the top 10 most profitable companies in the world. So take a look at the top 3 biotech companies below:

1. Johnson & Johnson

With a market cap of $385 billion and earnings in excess of $82 billion, J&J is undoubtedly at the top of the list of the top largest biotech companies in the world. The company comprises 250 subsidiaries operating in more than 60 countries. 

J&J has recently been well-known for several major judgments against it, most notably in relation to its famous baby powder, which is said to cause cancer in its users. But despite the findings against the company, with awards totaling billions of dollars, even that wasn't enough to demote it from the top spot.

2. F. Hoffmann-La Roche AG

Roche is based in Basel and was founded in 1896. It was the first biotech company to mass-produce vitamin C in 1934, while in 1957 it began producing tranquilizers, including the controversial Rohypnol, which later became famous as a date-rape drug. The first antidepressant was also created by Roche in 1956, albeit by mistake. It generated $63.85 billion in revenue in 2019.

3. Novartis

Novartis is a large biotech company in Sweden with a market capitalization of $240 billion. The company was founded in 1996 following the merger of Sandoz and Ciba-Geigy and has since grown into one of the world's largest companies. 

Although like other big pharmaceutical companies, it has faced scrutiny over controversial practices such as gender discrimination lawsuits and marketing violations, bribery, and also data-related scandals. Despite these controversies, its products continue to sell well, bringing the company $47.45 billion in sales in 2019.

Best Biotech Company To Work For

The above enterprises are highly recommended for their professional working environment and stable salary. They have visionary managers and friendly colleagues, so these will be perfect environments for you to develop yourself and still have a high salary.

Based on reviews from people who have worked there, we have a list of the top 3 best companies to work for:

1. Promega

Promega is a biotech company based in Madison, WI. The enterprise has about 1200 to 2000 employees. The company received top marks for promoting family development (4.7 stars) and paid leave (4.7 stars).

2. Eurofins Lancaster Laboratories

Eurofins Lancaster Laboratories is a biotechnology company with between 1,001 and 5,000 employees. The company has its highest marks in supporting diversity (4.6 stars) and the people it works with (4.5 stars).

3. Biogen

Biogen is a biotech company based in the Cambridge, MA area and employs between 5,001 and 10,000 employees. The company has top marks for supporting diversity (5.0 stars) and wellness initiatives (4.6 stars).

Related: Life Science Industry: Comprehensive and examples

Learn about Biotech Company

Biotechnology is currently one of the most modern, highest paying industries and is also facing a shortage of human resources. Above are the best and largest companies in the biotech industry, you can consult and decide which company to work at.

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